It has the least glamorous name in aesthetics and one of the fastest growing followings. PDRN, short for polydeoxyribonucleotide, is a DNA fragment usually derived from salmon. It is used in skin boosters and microneedling treatments aimed at repair, glow and texture.
How it is used
- Injected skin boosters such as Rejuran, placed in tiny amounts across the face.
- Microneedling with PDRN, where the serum is applied during or after needling.
- Sessions: 3, about 2 to 4 weeks apart
- Appointment: 45 to 60 minutes
- Downtime: Small bumps for 1 to 2 days
- Results: Build over 4 to 8 weeks
Who has talked about it
- Jennifer Aniston: Has spoken candidly about trying the salmon sperm facial, microneedling with salmon derived PDRN. Source: Via NewBeauty.
- Hilary Duff: Has talked about getting salmon sperm facials along with microneedling. Source: People, via NewBeauty.
What to ask
- Is it injected or topical with microneedling? Results and prices differ.
- Which product, and is it sourced from a licensed supplier?
- How many sessions are included in the quote?
We list 61 Manhattan practices offering salmon PDRN. Popular pairings include microneedling and HydraFacial.
Find it near you: see every Manhattan practice that offers salmon PDRN, with prices where they publish them, on our salmon PDRN guide.
On the record means the person said it themselves, in an interview, on their own show or on their own social account. We link every source. We never use celebrity photos to sell a practice, and nothing here is medical advice. Talk to a licensed provider about what is right for you.